Temsirolimus Sensitive Stimulation of Platelet Activity, Apoptosis and Aggregation by Collagen Related Peptide

Temsirolimus Sensitive Stimulation of Platelet Activity, Apoptosis and Aggregation by Collagen Related Peptide

Background/Aims: The mammalian target of rapamycin (mTOR) inhibitor temsirolimus stimulates apoptosis of tumor cells and is thus therapeutically used for the treatment of diverse malignancies. On the other hand, temsirolimus has been shown to protect against apoptosis of hippocampal neurons. Similar...

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Bibliographic Details
Main Authors: Hang Cao, Rosi Bissinger, Anja T. Umbach, Meinrad Gawaz, Florian Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
CRP
Platelet activation
Degranulation
Caspase
Phosphatidylserine translocation
Aggregation
Integrin
Cytosolic Ca2+ concentration
Online Access:http://www.karger.com/Article/FullText/478954

Internet

http://www.karger.com/Article/FullText/478954

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