B-1 cell immunoglobulin directed against oxidation-specific epitopes

Natural antibodies (NAbs) are pre-existing antibodies with germline origin that arise in the absence of previous exposure to foreign antigens. NAbs are produced by B-1 lymphocytes and are primarily of the IgM isotype. There is accumulating evidence that - in addition to their role in antimicrobial h...

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Bibliographic Details
Main Authors: Dimitrios eTsiantoulas, Sabrina eGruber, Christoph J. Binder
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00415/full