Ultraviolet A Enhances Cathepsin L Expression and Activity via JNK Pathway in Human Dermal Fibroblasts

Ultraviolet A Enhances Cathepsin L Expression and Activity via JNK Pathway in Human Dermal Fibroblasts

Background: Cathepsin L (CatL) is a cysteine protease with strong matrix degradation activity that contributes to photoaging. Mannose phosphate-independent sorting pathways mediate ultraviolet A (UVA)-induced alternate trafficking of CatL. Little is known about signaling pathways involved in the reg...

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Bibliographic Details
Main Authors: Qing-Fang Xu, Yue Zheng, Jian Chen, Xin-Ya Xu, Zi-Jian Gong, Yun-Fen Huang, Chun Lu, Howard I Maibach, Wei Lai
Format: Article
Language:English
Published: Wolters Kluwer 2016-01-01
Series:Chinese Medical Journal
Subjects:
Cathepsin L; JNK Pathway; Photoaging; Ultraviolet A
Online Access:http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=23;spage=2853;epage=2860;aulast=Xu

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http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=23;spage=2853;epage=2860;aulast=Xu

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