Chaperone-Mediated Autophagy Targets IFNAR1 for Lysosomal Degradation in Free Fatty Acid Treated HCV Cell Culture.

Hepatic steatosis is a risk factor for both liver disease progression and an impaired response to interferon alpha (IFN-α)-based combination therapy in chronic hepatitis C virus (HCV) infection. Previously, we reported that free fatty acid (FFA)-treated HCV cell culture induces hepatocellular steato...

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Bibliographic Details
Main Authors: Ramazan Kurt, Partha K Chandra, Fatma Aboulnasr, Rajesh Panigrahi, Pauline Ferraris, Yucel Aydin, Krzysztof Reiss, Tong Wu, Luis A Balart, Srikanta Dash
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4427131?pdf=render