Tcf7 is an important regulator of the switch of self-renewal and differentiation in a multipotential hematopoietic cell line.

Tcf7 is an important regulator of the switch of self-renewal and differentiation in a multipotential hematopoietic cell line.

A critical problem in biology is understanding how cells choose between self-renewal and differentiation. To generate a comprehensive view of the mechanisms controlling early hematopoietic precursor self-renewal and differentiation, we used systems-based approaches and murine EML multipotential hema...

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Bibliographic Details
Main Authors: Jia Qian Wu, Montrell Seay, Vincent P Schulz, Manoj Hariharan, David Tuck, Jin Lian, Jiang Du, Minyi Shi, Zhijia Ye, Mark Gerstein, Michael P Snyder, Sherman Weissman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3297581?pdf=render

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http://europepmc.org/articles/PMC3297581?pdf=render

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