Role of tumor suppressor p53 and micro-RNA interplay in multiple myeloma pathogenesis
Abstract The molecular mechanisms underlying dysregulated wild type (wt) p53 in multiple myeloma (MM) have been subjects of intense investigation for years. Indeed, correlation of rarely occurring TP53 gene mutations or deletions with adverse clinical outcomes in MM patients is strongly established,...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-10-01
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Series: | Journal of Hematology & Oncology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13045-017-0538-4 |