MOLECULAR DYNAMICS COMPUTER SIMULATIONS OF MULTIDRUG RND EFFLUX PUMPS

Over-expression of multidrug efflux pumps of the Resistance Nodulation Division (RND) protein super family counts among the main causes for microbial resistance against pharmaceuticals. Understanding the molecular basis of this process is one of the major challenges of modern biomedical research, in...

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Bibliographic Details
Main Authors: Paolo Ruggerone, Attilio V. Vargiu, Francesca Collu, Nadine Fischer, Christian Kandt
Format: Article
Language:English
Published: Elsevier 2013-02-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037014600362