New ISE-Based Apparatus for Na<sup>+</sup>, K<sup>+</sup>, Cl<sup>−</sup>, pH and Transepithelial Potential Difference Real-Time Simultaneous Measurements of Ion Transport across Epithelial Cells Monolayer–Advantages and Pitfalls

New ISE-Based Apparatus for Na<sup>+</sup>, K<sup>+</sup>, Cl<sup>−</sup>, pH and Transepithelial Potential Difference Real-Time Simultaneous Measurements of Ion Transport across Epithelial Cells Monolayer–Advantages and Pitfalls

Cystic Fibrosis (CF) is the most common fatal human genetic disease, which is caused by a defect in an anion channel protein (CFTR) that affects ion and water transport across the epithelium. We devised an apparatus to enable the measurement of concentration changes of sodium, potassium, chloride, p...

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Bibliographic Details
Main Authors: Mirosław Zając, Andrzej Lewenstam, Magdalena Stobiecka, Krzysztof Dołowy
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Sensors
Subjects:
ion-selective electrodes
epithelium
ion transport
cystic fibrosis
Online Access:https://www.mdpi.com/1424-8220/19/8/1881

Internet

https://www.mdpi.com/1424-8220/19/8/1881

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