Genome-wide specificity of dCpf1 cytidine base editors

Cas12a-linked base editors can broaden the targeting scope of programmable cytidine deaminases. Here the authors assess their target specificity in an in vitro genome-wide assay.

Bibliographic Details
Main Authors: Daesik Kim, Kayeong Lim, Da-eun Kim, Jin-Soo Kim
Format: Article
Language:English
Published: Nature Publishing Group 2020-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17889-9