Biocompatible nucleus-targeted graphene quantum dots for selective killing of cancer cells via DNA damage

Qi et al. develop nucleus targeting graphene quantum dots (GQDs) by modifying amine-functionalised GQDs with nucleus targeting TAT peptides. The resulting functionalised GQDs exhibit good biocompatibility, nucleus uptake, and cancer cell targeting. They can suppress growth of cancer cells by selecti...

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Bibliographic Details
Main Authors: Lei Qi, Tonghe Pan, Liling Ou, Zhiqiang Ye, Chunlei Yu, Bijun Bao, Zixia Wu, Dayong Cao, Liming Dai
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01713-1