Biocompatible nucleus-targeted graphene quantum dots for selective killing of cancer cells via DNA damage

Biocompatible nucleus-targeted graphene quantum dots for selective killing of cancer cells via DNA damage

Qi et al. develop nucleus targeting graphene quantum dots (GQDs) by modifying amine-functionalised GQDs with nucleus targeting TAT peptides. The resulting functionalised GQDs exhibit good biocompatibility, nucleus uptake, and cancer cell targeting. They can suppress growth of cancer cells by selecti...

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Bibliographic Details
Main Authors: Lei Qi, Tonghe Pan, Liling Ou, Zhiqiang Ye, Chunlei Yu, Bijun Bao, Zixia Wu, Dayong Cao, Liming Dai
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01713-1
Description
Summary:Qi et al. develop nucleus targeting graphene quantum dots (GQDs) by modifying amine-functionalised GQDs with nucleus targeting TAT peptides. The resulting functionalised GQDs exhibit good biocompatibility, nucleus uptake, and cancer cell targeting. They can suppress growth of cancer cells by selectively inducing DNA damage.
ISSN:2399-3642

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