The silencing of LncRNA-H19 decreases chemoresistance of human glioma cells to temozolomide by suppressing epithelial-mesenchymal transition via the Wnt/β-Catenin pathway

The silencing of LncRNA-H19 decreases chemoresistance of human glioma cells to temozolomide by suppressing epithelial-mesenchymal transition via the Wnt/β-Catenin pathway

Linwei Jia, Yaohui Tian, Yonghan Chen, Gang Zhang Department of Neurosurgery, CangZhou Central Hospital, Hebei, China Introduction: Temozolomide (TMZ) is commonly used for glioma chemotherapy. However, TMZ resistance limits the therapeutic effect of TMZ in glioma treatment. LncRNA-H19 acts as an o...

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Bibliographic Details
Main Authors: Jia L, Tian Y, Chen Y, Zhang G
Format: Article
Language:English
Published: Dove Medical Press 2018-01-01
Series:OncoTargets and Therapy
Subjects:
LncRNA-H19
chemoresistance
glioma
temozolomide
EMT
Wnt/β-Catenin
Online Access:https://www.dovepress.com/the-silencing-of-lncrna-h19-decreases-chemoresistance-of-human-glioma--peer-reviewed-article-OTT

Internet

https://www.dovepress.com/the-silencing-of-lncrna-h19-decreases-chemoresistance-of-human-glioma--peer-reviewed-article-OTT

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