Sickle cell disease complications

Sickle cell disease (SCD) is an inherited, lifelong condition. The sickle mutation consists a single nucleotide change (GAT->GTT) in the sixth codon of exon 1 of the β-globin gene coding for the β-globin polypeptide of hemoglobin (Hb) (a2β2). This change results in replacement of the wild typ...

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Bibliographic Details
Main Author: Ersi Voskaridou
Format: Article
Language:English
Published: PAGEPress Publications 2014-12-01
Series:Thalassemia Reports
Subjects:
Online Access:http://www.pagepressjournals.org/index.php/thal/article/view/4873