Reproduction and In-Depth Evaluation of Genome-Wide Association Studies and Genome-Wide Meta-analyses Using Summary Statistics

Reproduction and In-Depth Evaluation of Genome-Wide Association Studies and Genome-Wide Meta-analyses Using Summary Statistics

In line with open-source genetics, we report a novel linear regression technique for genome-wide association studies (GWAS), called Open GWAS algoriTHm (OATH). When individual-level data are not available, OATH can not only completely reproduce reported results from an experimental model, but also r...

Full description

Bibliographic Details
Main Authors: Yao-Fang Niu, Chengyin Ye, Ji He, Fang Han, Long-Biao Guo, Hou-Feng Zheng, Guo-Bo Chen
Format: Article
Language:English
Published: Oxford University Press 2017-03-01
Series:G3: Genes, Genomes, Genetics
Subjects:
GWAS
Arabidopsis
magnesium
transparency
reproducibility
naïve summary statistics
meta-analyses
GWAMA
GEAR
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.038877

Internet

http://g3journal.org/lookup/doi/10.1534/g3.116.038877

Similar Items