2-BFI Provides Neuroprotection Against Inflammation and Necroptosis in a Rat Model of Traumatic Brain Injury

2-BFI Provides Neuroprotection Against Inflammation and Necroptosis in a Rat Model of Traumatic Brain Injury

Inflammation and programmed necrosis (necroptosis) are the two hallmark pathological changes after traumatic brain injury (TBI) that contribute to aggravated brain damage. 2-(2-Benzofuranyl)-2-imidazoline (2-BFI) has been shown to exert both anti-inflammatory and programmed cell death effects. There...

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Bibliographic Details
Main Authors: Haibo Ni, Qin Rui, Xiaolong Lin, Di Li, Huixiang Liu, Gang Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Neuroscience
Subjects:
2-BFI
inflammation
necroptosis
neuroprotection
traumatic brain injury
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00674/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2019.00674/full

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