Reverse phase high-performance liquid chromatography for quantification of hydroxymethylnitrofurazone in polymeric nanoparticles

Hydroxymethylnitrofurazone (NFOH) is a new compound with potential leishmanicidal and trypanocidal activity. Despite its effectiveness, the formulators have to overcome its poor aqueous solubility. Recently, polymeric nano-scale drug delivery systems have proposed for the treatment of neglected dise...

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Bibliographic Details
Main Authors: Lis Marie Monteiro, Guilherme Diniz Tavares, Elizabeth Igne Ferreira, Vladi Olga Consiglieri, Nadia Araci Bou-Chacra, Raimar Löbenberg
Format: Article
Language:English
Published: Universidade de São Paulo 2015-09-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000300561&lng=en&tlng=en