Evaluation of basophil activation caused by transgenic rice seeds expressing whole T cell epitopes of the major Japanese cedar pollen allergens

Evaluation of basophil activation caused by transgenic rice seeds expressing whole T cell epitopes of the major Japanese cedar pollen allergens

Abstract Background Japanese cedar (JC) pollinosis is a serious type I allergic disease in Japan. Although subcutaneous immunotherapy and sublingual immunotherapy have been applied to treat JC pollinosis, high doses of allergens may cause IgE-mediated allergic reactions. The transgenic rice seeds th...

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Bibliographic Details
Main Authors: Shinya Takaishi, Saburo Saito, Minori Kamada, Nobuyoshi Otori, Hiromi Kojima, Kenjiro Ozawa, Fumio Takaiwa
Format: Article
Language:English
Published: Wiley 2019-02-01
Series:Clinical and Translational Allergy
Subjects:
Pollinosis
Immunotherapy
T-cell epitope
Transgenic rice
Basophil activation test
Online Access:http://link.springer.com/article/10.1186/s13601-019-0249-8

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http://link.springer.com/article/10.1186/s13601-019-0249-8

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