Assessing technical and biological variation in SWATH-MS-based proteomic analysis of chronic lymphocytic leukaemia cells

Assessing technical and biological variation in SWATH-MS-based proteomic analysis of chronic lymphocytic leukaemia cells

Abstract Chronic lymphocytic leukaemia (CLL) exhibits variable clinical course and response to therapy, but the molecular basis of this variability remains incompletely understood. Data independent acquisition (DIA)-MS technologies, such as SWATH (Sequential Windowed Acquisition of all THeoretical f...

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Bibliographic Details
Main Authors: Gina L. Eagle, John M. J. Herbert, Jianguo Zhuang, Melanie Oates, Umair T. Khan, Neil R. Kitteringham, Kim Clarke, B. Kevin Park, Andrew R. Pettitt, Rosalind E. Jenkins, Francesco Falciani
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-82609-2

Internet

https://doi.org/10.1038/s41598-021-82609-2

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