Translating natural genetic variation to gene expression in a computational model of the Drosophila gap gene regulatory network.

Translating natural genetic variation to gene expression in a computational model of the Drosophila gap gene regulatory network.

Annotating the genotype-phenotype relationship, and developing a proper quantitative description of the relationship, requires understanding the impact of natural genomic variation on gene expression. We apply a sequence-level model of gap gene expression in the early development of Drosophila to an...

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Bibliographic Details
Main Authors: Vitaly V Gursky, Konstantin N Kozlov, Ivan V Kulakovskiy, Asif Zubair, Paul Marjoram, David S Lawrie, Sergey V Nuzhdin, Maria G Samsonova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5595321?pdf=render

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http://europepmc.org/articles/PMC5595321?pdf=render

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