Mesenchymal Stem Cells Pretreated with HGF and FGF4 Can Reduce Liver Fibrosis in Mice

Stem cells have opened a new avenue to treat liver fibrosis. We investigated in vitro and in vivo the effect of cytokine (HGF and FGF4) pretreated MSCs in reduction of CCl4 liver injury. Mouse MSCs were pretreated with cytokines to improve their ability to reduce CCl4 injury. In vitro we gave CCl4 i...

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Bibliographic Details
Main Authors: Sulaiman Shams, Sadia Mohsin, Ghazanfar Ali Nasir, Mohsin Khan, Shaheen N. Khan
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2015/747245