Disease progression and phasic changes in gene expression in a mouse model of osteoarthritis.

Osteoarthritis (OA) is the most common form of arthritis and has multiple risk factors including joint injury. The purpose of this study was to characterize the histologic development of OA in a mouse model where OA is induced by destabilization of the medial meniscus (DMM model) and to identify gen...

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Bibliographic Details
Main Authors: Richard F Loeser, Amy L Olex, Margaret A McNulty, Cathy S Carlson, Michael Callahan, Cristin Ferguson, Jacquelyn S Fetrow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3557277?pdf=render