Downregulation of miR-322 promotes apoptosis of GC-2 cell by targeting Ddx3x

Abstract Background Aberrant DNA damage of germ cells, which impairs spermatogenesis and lowers fertility, is an important factor contributing to male infertility. MicroRNAs (miRNAs) play a significant role in the expression and regulation of multiple genes during spermatogenesis. Our previous study...

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Bibliographic Details
Main Authors: Qi Che, Wei Wang, Peng Duan, Fang Fang, Chunyan Liu, Ting Zhou, Honggang Li, Chengling Xiong, Kai Zhao
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Reproductive Biology and Endocrinology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12958-019-0506-7