R-CHOP resistance in diffuse large B-cell lymphoma: biological and molecular mechanisms

Abstract. Although the first-line rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone regimen (R-CHOP) substantially improved outcomes for patients with diffuse large B-cell lymphoma (DLBCL), 40% of the patients suffered from relapsed/refractory disease and had poor survival ou...

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Bibliographic Details
Main Authors: Liang Wang, Lin-Rong Li, Peng Lyu
Format: Article
Language:English
Published: Wolters Kluwer 2021-02-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000001294