L-arginine and tetrahydrobiopterin modulate endothelin-1A receptor activity in isolated rat aorta

Endothelin-1 (ET-1), is a potent endogenous vasoconstrictor secreted by endothelial cells. It acts as the natural counterpart of the vasodilator effect of nitric oxide (NO). ET-1 exert it is the vasoconstrictor activity through two types of receptors, ET-1A and ET-1B receptors that are located on va...

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Bibliographic Details
Main Authors: Zhikal Omar Khidhr, Ismail Mustafa Maulood, professor
Format: Article
Language:English
Published: Salahaddin University-Erbil 2019-04-01
Series:Zanco Journal of Pure and Applied Sciences
Subjects:
Online Access:https://zancojournals.su.edu.krd/index.php/JPAS/article/view/2670