Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice

Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice

Abstract Background Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by an abnormal accumulation of amyloid-β (Aβ) plaques, neuroinflammation, and impaired neurogenesis. Urolithin A (UA), a gut-microbial metabolite of ellagic acid, has been reported to exert anti-in...

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Bibliographic Details
Main Authors: Zhuo Gong, Jingyi Huang, Biao Xu, Zhenri Ou, Le Zhang, Xiaohong Lin, Xiujuan Ye, Xuejian Kong, Dahong Long, Xiangdong Sun, Xiaosong He, Liping Xu, Qingqing Li, Aiguo Xuan
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Journal of Neuroinflammation
Subjects:
Alzheimer’s disease
Urolithin A
Neuroinflammation
Memory impairment
Neurogenesis
Online Access:http://link.springer.com/article/10.1186/s12974-019-1450-3

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http://link.springer.com/article/10.1186/s12974-019-1450-3

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