In vitro Evaluation of the Anti-inflammatory Effects of Thymoquinone in Osteoarthritis and in silico Analysis of Inter-Related Pathways in Age-Related Degenerative Diseases

In vitro Evaluation of the Anti-inflammatory Effects of Thymoquinone in Osteoarthritis and in silico Analysis of Inter-Related Pathways in Age-Related Degenerative Diseases

Chronic inflammation is a common underlying factor in osteoarthritis (OA) and most age-related degenerative diseases. As conventional therapies help only in partial alleviation of symptoms in OA, stem cell-based therapies and herbal supplements are being widely explored. Thymoquinone (TQ), an active...

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Bibliographic Details
Main Authors: Gauthaman Kalamegam, Saadiah M. Alfakeeh, Afnan Omar Bahmaid, Etimad A. AlHuwait, Mamdouh A. Gari, Mohammed M. Abbas, Farid Ahmed, Muhammed Abu-Elmagd, Peter Natesan Pushparaj
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
stem cells
osteoarthritis
thymoquinone
inflammation
aging
ingenuity pathway analysis
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00646/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00646/full

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