pH-sensitive niosomes: Effects on cytotoxicity and on inflammation and pain in murine models

pH-sensitive niosomes: Effects on cytotoxicity and on inflammation and pain in murine models

pH-sensitive nonionic surfactant vesicles (niosomes) by polysorbate-20 (Tween-20) or polysorbate-20 derivatized by glycine (added as pH sensitive agent), were developed to deliver Ibuprofen (IBU) and Lidocaine (LID). For the physical-chemical characterization of vesicles (mean size, size distributio...

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Bibliographic Details
Main Authors: Federica Rinaldi, Elena Del Favero, Valeria Rondelli, Stefano Pieretti, Alessia Bogni, Jessica Ponti, François Rossi, Luisa Di Marzio, Donatella Paolino, Carlotta Marianecci, Maria Carafa
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
pH-sensitive niosomes
lidocaine
ibuprofen
cytotoxicity
anti-nociceptive/anti-inflammatory activity
Online Access:http://dx.doi.org/10.1080/14756366.2016.1268607

Internet

http://dx.doi.org/10.1080/14756366.2016.1268607

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