S-Nitrosothiol Signaling Regulates Liver Development and Improves Outcome following Toxic Liver Injury

Toxic liver injury is a leading cause of liver failure and death because of the organ’s inability to regenerate amidst massive cell death, and few therapeutic options exist. The mechanisms coordinating damage protection and repair are poorly understood. Here, we show that S-nitrosothiols regulate li...

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Bibliographic Details
Main Authors: Andrew G. Cox, Diane C. Saunders, Peter B. Kelsey Jr., Allie A. Conway, Yevgenia Tesmenitsky, Julio F. Marchini, Kristin K. Brown, Jonathan S. Stamler, Dorothy B. Colagiovanni, Gary J. Rosenthal, Kevin J. Croce, Trista E. North, Wolfram Goessling
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713007523