Identification of disease-distinct complex biomarker patterns by means of unsupervised machine-learning using an interactive R toolbox (Umatrix)

Abstract Background Unsupervised machine-learned analysis of cluster structures, applied using the emergent self-organizing feature maps (ESOM) combined with the unified distance matrix (U-matrix) has been shown to provide an unbiased method to identify true clusters. It outperforms classical hierar...

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Bibliographic Details
Main Authors: Jörn Lötsch, Florian Lerch, Ruth Djaldetti, Irmgard Tegder, Alfred Ultsch
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Big Data Analytics
Online Access:http://link.springer.com/article/10.1186/s41044-018-0032-1