Identification of a conserved virion-stabilizing network inside the interprotomer pocket of enteroviruses

Flatt, Butcher and colleagues use cryo-EM to report on coxsackieviruses B3 and B4 bound to different capsid binders. Comparative analysis revealed the residues that form a conserved virion stabilizing network at the interprotomer site, and showed the small molecule properties that allow anchoring in...

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Bibliographic Details
Main Authors: Justin W. Flatt, Aušra Domanska, Alma L. Seppälä, Sarah J. Butcher
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01779-x