Concise Review: Application of Chemically Modified mRNA in Cell Fate Conversion and Tissue Engineering

Abstract Chemically modified RNA (cmRNA) has potential as a safe and efficient tool for nucleic acid‐based therapies and regenerative medicine. Modifications in the chemistry of mRNA can enhance stability, reduce immunogenicity, and thus facilitate mRNA‐based nucleic acid therapy, which eliminates r...

Full description

Bibliographic Details
Main Authors: Zohreh Sadat Badieyan, Todd Evans
Format: Article
Language:English
Published: Wiley 2019-08-01
Series:Stem Cells Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/sctm.18-0259