The Development and Characterization of an HEK293-Derived Cell Line for Use in an Intratumoral Cytokine Delivery System

As part of ongoing work to develop a method of cytokine delivery for use as an intratumoral depot, we noted that HEK293 cells, encapsulated in alginate, died within 24–48 h after in vivo, intratumoral implantation. We hypothesized that the highly hypoxic and acidic conditions found inside the tumor...

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Bibliographic Details
Main Authors: M. J. Hamilton, Q. X. Huang, C. L. Li, K. A. O. Ellem
Format: Article
Language:English
Published: SAGE Publishing 2006-04-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000006783981891