The Development and Characterization of an HEK293-Derived Cell Line for Use in an Intratumoral Cytokine Delivery System
As part of ongoing work to develop a method of cytokine delivery for use as an intratumoral depot, we noted that HEK293 cells, encapsulated in alginate, died within 24–48 h after in vivo, intratumoral implantation. We hypothesized that the highly hypoxic and acidic conditions found inside the tumor...
Main Authors: | M. J. Hamilton, Q. X. Huang, C. L. Li, K. A. O. Ellem |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2006-04-01
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Series: | Cell Transplantation |
Online Access: | https://doi.org/10.3727/000000006783981891 |
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