IL-15 and IL15RA in Osteoarthritis: Association With Symptoms and Protease Production, but Not Structural Severity

IL-15 and IL15RA in Osteoarthritis: Association With Symptoms and Protease Production, but Not Structural Severity

Objective: Interleukin-15 (IL-15) is a pro-inflammatory cytokine that is increased in joint fluids of early-stage osteoarthritis (OA) patients, and has been associated with expression of proteases that can damage cartilage, and the development of neuropathic pain-like symptoms (NP) after nerve injur...

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Bibliographic Details
Main Authors: Sophie C. Warner, Anjali Nair, Rahul Marpadga, Susan Chubinskaya, Michael Doherty, Ana M. Valdes, Carla R. Scanzello
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
Subjects:
inflammation
pain
proteases
interleukins
interleukin-15
osteoarthritis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01385/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01385/full

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