Dapagliflozin attenuates hypoxia/reoxygenation-caused cardiac dysfunction and oxidative damage through modulation of AMPK

Abstract Background Emerging evidence demonstrated dapagliflozin (DAPA), a sodium-glucose cotransporter 2 inhibitor, prevented various cardiovascular events. However, the detailed mechanisms underlying its cardioprotective properties remained largely unknown. Results In the present study, we sought...

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Bibliographic Details
Main Authors: Kun-Ling Tsai, Pei-Ling Hsieh, Wan-Ching Chou, Hui-Ching Cheng, Yu-Ting Huang, Shih-Hung Chan
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Cell & Bioscience
Subjects:
Online Access:https://doi.org/10.1186/s13578-021-00547-y