Flavonoids from Orostachys japonicus A. Berger Inhibit the Invasion of LnCaP Prostate Carcinoma Cells by Inactivating Akt and Modulating Tight Junctions

Flavonoids from Orostachys japonicus A. Berger Inhibit the Invasion of LnCaP Prostate Carcinoma Cells by Inactivating Akt and Modulating Tight Junctions

Tight junctions (TJs) are a mode of cell-to-cell adhesion in epithelial or endothelial cells, and serve as a physical barrier to maintenance of homeostasis in body by controlling paracellular transport. Claudins are the most important molecules of the TJs, but paradoxically these proteins are freque...

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Bibliographic Details
Main Authors: Soon Chan Hong, Sung Chul Shin, Chung Ho Ryu, Jin-Myung Jung, Gon Sup Kim, Hye Jin Hwang, Gi-Young Kim, Hye Jung Kim, Cheol Park, Su Hyun Hong, Ji Hyun Jung, Dong Yeok Shin, Won Sup Lee, Yung Hyun Choi
Format: Article
Language:English
Published: MDPI AG 2013-09-01
Series:International Journal of Molecular Sciences
Subjects:
Orostachys japonicus
flavonoids
LnCaP cells
tight junctions
Akt
Online Access:http://www.mdpi.com/1422-0067/14/9/18407

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http://www.mdpi.com/1422-0067/14/9/18407

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