Lossen Rearrangement of p-Toluenesulfonates of N-Oxyimides in Basic Condition, Theoretical Study, and Molecular Docking

Lossen Rearrangement of p-Toluenesulfonates of N-Oxyimides in Basic Condition, Theoretical Study, and Molecular Docking

The sulfonic esters of N-oxyimides are a group of compounds with a wide range of biological activities, as well as a unique reactivity toward amines. They undergo this reaction with primary amines and other nucleophilic reagents according to a Lossen-like rearrangement. The reaction is initiated by...

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Bibliographic Details
Main Authors: Monika Kijewska, Abeer A. Sharfalddin, Łukasz Jaremko, Marta Cal, Bartosz Setner, Miłosz Siczek, Piotr Stefanowicz, Mostafa A. Hussien, Abdul-Hamid Emwas, Mariusz Jaremko
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Chemistry
Subjects:
p-toluenesulfonates
N-oxyimides
XRD
NMR
DFT
molecular docking
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2021.662533/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2021.662533/full

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