Triggering of protection mechanism against Phoneutria nigriventer spider venom in the brain.

Severe accidents caused by the "armed" spider Phoneutria nigriventer cause neurotoxic manifestations in victims. In experiments with rats, P. nigriventer venom (PNV) temporarily disrupts the properties of the BBB by affecting both the transcellular and the paracellular route. However, it i...

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Bibliographic Details
Main Authors: Catarina Rapôso, Paulo Alexandre Miranda Odorissi, Stefania Fioravanti Savioli, Rafaela Chitarra Rodrigues Hell, Gustavo Ferreira Simões, Roberta R Ruela-de-Sousa, Alexandre Leite Rodrigues de Oliveira, Maria Alice da Cruz-Höfling
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0107292