Intrinsic Immune Mechanisms Restricting Human Cytomegalovirus Replication

Cellular restriction factors (RFs) act as important constitutive innate immune barriers against viruses. In 2006, the promyelocytic leukemia protein was described as the first RF against human cytomegalovirus (HCMV) infection which is antagonized by the viral immediate early protein IE1. Since then,...

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Bibliographic Details
Main Authors: Eva-Maria Schilling, Myriam Scherer, Thomas Stamminger
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/13/2/179