Cell Cycle Arrest and Apoptosis Induction by a New 2,4-Dinitrobenzenesulfonamide Derivative In Acute Leukemia Cells

Cell Cycle Arrest and Apoptosis Induction by a New 2,4-Dinitrobenzenesulfonamide Derivative In Acute Leukemia Cells

Background: Current therapies for acute leukemias (ALs) are associated with severe adverse reactions and high relapse rates, which makes the search for new antileukemic agents a necessity. Therefore, the aim of this study was to evaluate the effects of a new sulfonamide, S1, in AL cells K562 and Ju...

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Main Authors: Patricia Alves Almeida, Luiz Felipe Schmitz de Souza, Mariana Franzoni Maioral, Laura Otto Walter, Bruna Fischer Duarte, Íris Mattos Santos-Pirath, Douglas Bauer Speer, Larissa Sens, Tiago Tizziani, Aldo Sena de Oliveira, Ricardo José Nunes, Maria Cláudia Santos-Silva
Format: Article
Language:English
Published: Canadian Society for Pharmaceutical Sciences 2021-01-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/31349

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https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/31349

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