C-Terminal Clostridium perfringens Enterotoxin-Mediated Antigen Delivery for Nasal Pneumococcal Vaccine.

C-Terminal Clostridium perfringens Enterotoxin-Mediated Antigen Delivery for Nasal Pneumococcal Vaccine.

Efficient vaccine delivery to mucosal tissues including mucosa-associated lymphoid tissues is essential for the development of mucosal vaccine. We previously reported that claudin-4 was highly expressed on the epithelium of nasopharynx-associated lymphoid tissue (NALT) and thus claudin-4-targeting u...

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Bibliographic Details
Main Authors: Hidehiko Suzuki, Akihiro Watari, Eri Hashimoto, Miki Yonemitsu, Hiroshi Kiyono, Kiyohito Yagi, Masuo Kondoh, Jun Kunisawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4446347?pdf=render

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http://europepmc.org/articles/PMC4446347?pdf=render

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