Toll-like receptor 4 (TLR4) expression in human and murine pancreatic beta-cells affects cell viability and insulin homeostasis

Toll-like receptor 4 (TLR4) expression in human and murine pancreatic beta-cells affects cell viability and insulin homeostasis

<p>Abstract</p> <p>Background</p> <p>Toll-like receptor 4 (TLR4) is widely recognized as an essential element in the triggering of innate immunity, binding pathogen-associated molecules such as Lipopolysaccharide (LPS), and in initiating a cascade of pro-inflammatory ev...

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Bibliographic Details
Main Authors: Santos Icaro A, Mantovani Marluce, Mourão Roberta F, Garay-Malpartida Humberto M, Sogayar Mari C, Goldberg Anna C
Format: Article
Language:English
Published: BMC 2011-02-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/12/18

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http://www.biomedcentral.com/1471-2172/12/18

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