Toll-like receptor 4 (TLR4) expression in human and murine pancreatic beta-cells affects cell viability and insulin homeostasis
<p>Abstract</p> <p>Background</p> <p>Toll-like receptor 4 (TLR4) is widely recognized as an essential element in the triggering of innate immunity, binding pathogen-associated molecules such as Lipopolysaccharide (LPS), and in initiating a cascade of pro-inflammatory ev...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-02-01
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Series: | BMC Immunology |
Online Access: | http://www.biomedcentral.com/1471-2172/12/18 |