Filipin recognizes both GM1 and cholesterol in GM1 gangliosidosis mouse brain

Filipin recognizes both GM1 and cholesterol in GM1 gangliosidosis mouse brain

Filipin is an antibiotic polyene widely used as a histochemical marker for cholesterol. We previously reported cholesterol/filipin-positive staining in brain of β-galactosidase (β-gal) knockout (−/−) mice (GM1 gangliosidosis). The content and distribution of cholesterol and gangliosides was analyzed...

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Bibliographic Details
Main Authors: Julian R. Arthur, Karie A. Heinecke, Thomas N. Seyfried
Format: Article
Language:English
Published: Elsevier 2011-07-01
Series:Journal of Lipid Research
Subjects:
cholesterol/trafficking
ganglioside
lipid raft
phospholipid/phosphatidylcholine
phospholipid/phosphatidylethanolamine
sphingolipid
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520370280

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http://www.sciencedirect.com/science/article/pii/S0022227520370280

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