Targeting GRB7/ERK/FOXM1 signaling pathway impairs aggressiveness of ovarian cancer cells.

Targeting GRB7/ERK/FOXM1 signaling pathway impairs aggressiveness of ovarian cancer cells.

Ovarian cancer is a highly lethal disease with poor prognosis and especially in high-grade tumor. Emerging evidence has reported that aberrant upregulation and activation of GRB7, ERK as well as FOXM1 are closely associated with aggresivenesss of human cancers. However, the interplay between these f...

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Bibliographic Details
Main Authors: David W Chan, Winnie W Y Hui, Patty C H Cai, Michelle X Liu, Mingo M H Yung, Celia S L Mak, Thomas H Y Leung, Karen K L Chan, Hextan Y S Ngan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3527599?pdf=render

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http://europepmc.org/articles/PMC3527599?pdf=render

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