Determination of phenobarbital in human plasma by a specific liquid chromatography method: application to a bioequivalence study
A liquid chromatography method was developed and validated for the determination of phenobarbital in human plasma using phenytoin as internal standard. The drugs were extracted from plasma by liquid-liquid extraction and separated isocratically on a C12 analytical column, maintained at 35 ºC, with w...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Sociedade Brasileira de Química
2010-01-01
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Series: | Química Nova |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422010000100023 |