Fibroblast growth factor receptor 1 gene amplification and protein expression in human lung cancer

Fibroblast growth factor receptor 1 gene amplification and protein expression in human lung cancer

Abstract Background Targeting fibroblast growth factor receptor 1 (FGFR1) is a potential treatment for squamous cell lung cancer (SQCLC). So far, treatment decision in clinical studies is based on gene amplification. However, only a minority of patients have shown durable response. Furthermore, form...

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Bibliographic Details
Main Authors: Omar Elakad, Anna‐Maria Lois, Katja Schmitz, Sha Yao, Sara Hugo, Laura Lukat, Marc Hinterthaner, Bernhard C. Danner, Alexander vonHammerstein‐Equord, Kirsten Reuter‐Jessen, Hans‐Ulrich Schildhaus, Philipp Ströbel, Hanibal Bohnenberger
Format: Article
Language:English
Published: Wiley 2020-05-01
Series:Cancer Medicine
Subjects:
CRISPR/Cas9
FGFR1
fluorescence in situ hybridization
immunohistochemistry
lung cancer
Online Access:https://doi.org/10.1002/cam4.2994

Internet

https://doi.org/10.1002/cam4.2994

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