Canstatin induces apoptosis in gastric cancer xenograft growth in mice through the mitochondrial apoptotic pathway

Canstatin, the non-collagenous domain of collagen type IV α-chains, belongs to a series of collagen-derived angiogenic inhibitors. In this study, the inhibitory effect of recombinant canstatin on tumour growth was investigated using a gastric cancer xenograft model. The volume and weight of tumours...

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Bibliographic Details
Main Authors: Ya‑Nan Xing, Peng Deng, Hui‑Mian Xu
Format: Article
Language:English
Published: Portland Press, Biochemical Society 2014-04-01
Series:Bioscience Reports
Subjects:
Online Access:http://www.bioscirep.org/bsr/034/e106/bsr034e106.htm