SRGN Promotes Colorectal Cancer Metastasis as a Critical Downstream Target of HIF-1α

Background/Aims: The chondroitin sulfate proteoglycan serglycin (SRGN), a hematopoietic cell granule proteoglycan, has been implicated in promoting tumor metastasis; however, the underlying mechanisms remain to be elucidated. The present study aimed to investigate the SRGN gene expression and its re...

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Bibliographic Details
Main Authors: Yang Xu, Jie  Xu, Yanfang Yang, Lei Zhu, Xubin Li, Weipeng Zhao
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
EMT
Online Access:https://www.karger.com/Article/FullText/492657