Methods for isolation and transcriptional profiling of individual cells from the human heart

Background: Global transcriptional profiling of individual cells represents a powerful approach to systematically survey contributions from cell-specific molecular phenotypes to human disease states but requires tissue-specific protocols. Here we sought to comprehensively evaluate protocols for sing...

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Bibliographic Details
Main Authors: Neha Pimpalwar, Tomasz Czuba, Maya Landenhed Smith, Johan Nilsson, Olof Gidlöf, J. Gustav Smith
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020326530